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  • #1

    Colonoscopy question

    Hi guys.
    I know this is a prostate forum but I thought who better to ask than you guys. Had my first colonoscopy last Friday. I'm still waiting on results but I'm a bit nervous. My Dr said no worries after I spoke with him the day of the procedure. But I had one 5mm polyp that was removed. He said it was sessile which means flat and not on a staulk. Is that large? Is one bad? Any information provided in yall experience would be nice.
    Wife posting - DOB 5/76- Black Male

    PSA Hist:
    1/2018 2.66
    1/2019 3.39
    Retest 2/019 3.04

    MRI 3/2019: 3 Lesions identified (1) Pirads 4 & (2)Pirads3
    MRI Guided Biopsy 4/11/2019: G6(3+3)

    RMB: 10% of 1 core
    RMM: 10% of the tissue (fragmented specimen).
    RMA: High-grade prostatic intraepithelial neoplasia.
    RLB: 25% of 1 core.
    RLM: 70% of tissue
    RLA: 50% of 1 core.
    LMB: 80% of 1 core.
    Lesion #2, in 3 of 3 cores, 80% of total tissue

    RALP 6/5/19 USMD Arlington Dr. R. Parham
    Cath 6 days, bladder spasms, cath back in for 5 days
    No incontinence/Minimum ED (using Sildenafil as needed)

    Final Path 6/11/19: G6(3+3)
    SV, BNI, Adipose Tissue, ECE, Margins, PNI, LVI, LNI(0of8) All Negative

    PT2N0 ~10% involved by tumor

    Quest Diagnostics uPSA:
    9/7/19 (3mths) <0.02
    1/4/20 (7mths) <0.1 & <0.02
    1/20/20 Annual physical <0.02
    6/6/20 (1yr) <0.02
    12/5/20(18mths) <0.02
    6/5/21(2Yr) <0.1
    1/17/22(31mths) 0.009-Clinical Path Lab ultrasensitive
    6/9/22(3 years)<0.04


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    Tags: None
  • #2
    Sessile polyps grow flat against the lining of the colon. They are type of polyp that can become cancerous and therefore should be removed, as opposed to the type of polyp that cannot progress. My own experience is that whenever the former were found (and removed), I've been asked to have my next colonoscopy in 3 years; with the latter, in 5 years. Your mileage may vary 😀

    Both of my parents had colon cancer. At one of my recent regular colonoscopies the nurse checking me in looked at my electronic chart and said "Well, you're not going to die of prostate cancer!:

    Djin
    Last edited by DjinTonic; 08-02-2022, 03:08 PM.
    69 yr at diagnosis, BPH x 20 yr, 9 (!) negative biopsies, PCA3-
    7-05-13 TURP for BPH (90→30 g) path negative for PCa, then 6-mo. checks
    6-06-17 Nodule on right + PSA rise on finasteride: 3.6→4.3
    6-28-17 Bx #10: 2/14 cores: G10 (5+5) 50% RB, G9 (4+5) 3% RLM
    Nodule was negative for PCa
    Bone scan, CTs, X-rays: neg.
    8-7-17 Open RP, negative frozen sections, Duke Regional Hosp.
    SM EPE BNI LVI SVI LNI(5L, 11R): negative, PNI+, nerves spared
    pT2c pN0 pMX, G9 (4+5) acinar adenocarcinoma
    5% of prostate (4.5 x 5 x 4 cm, 64 g) involved
    Dry; ED OK with sildenafil
    11-10-17 Decipher score: 0.37, Low Risk:
    5-yr met risk: 2.4%, 10-yr PCa-specific mortality: 3.3%    		 9-16-17 (5 wk) PSA <0.1
    LabCorp uPSA:
    11-28-17 (3 m ) 0.010
    02-26-18 (6 m ) 0.009
    05-30-18 (9 m ) 0.007 (nadir)
    08-27-18 (1 yr.) 0.018 (?)
    09-26-18 (13 m) 0.013 (retest)
    11-26-18 (15 m) 0.012
    02-25-19 (18 m) 0.015
    05-22-19 (21 m) 0.015
    08-28-19 (2 yr. ) 0.016
    12-18-19 (28 m) 0.015
    06-30-20 (34 m) <0.014
    12-30-20 (40 m) 0.037 (?)
    03-31-21 (43 m) 0.020
    07-13-21(46 m) 0.018
    01-25-22 (52 m) 0.023
    07-25-22 (5 yr) 0.039

    Comment

    • #3
      Originally posted by DjinTonic View Post
      Sessile polyps grow flat against the lining of the colon. They are type of polyp that can become cancerous and therefore should be removed, as opposed to the type of polyp that cannot progress. My own experience is that whenever the former were found (and removed), I've been asked to have my next colonoscopy in 3 years; with the latter, in 5 years. Your mileage may vary 😀

      Both of my parents had colon cancer. At one of my recent regular colonoscopies the nurse checking me in looked at my electronic chart and said "Well, you're not going to die of prostate cancer!:

      Djin
      Wow..... Ho many polyps did your Dr find? He told me 99.9% sure it's nothing being so small but after husband prostate cancer, I get so worried. Worrying is something I've haven't mastered not to do get. I hope I get results soon
      Wife posting - DOB 5/76- Black Male

      PSA Hist:
      1/2018 2.66
      1/2019 3.39
      Retest 2/019 3.04

      MRI 3/2019: 3 Lesions identified (1) Pirads 4 & (2)Pirads3
      MRI Guided Biopsy 4/11/2019: G6(3+3)

      RMB: 10% of 1 core
      RMM: 10% of the tissue (fragmented specimen).
      RMA: High-grade prostatic intraepithelial neoplasia.
      RLB: 25% of 1 core.
      RLM: 70% of tissue
      RLA: 50% of 1 core.
      LMB: 80% of 1 core.
      Lesion #2, in 3 of 3 cores, 80% of total tissue

      RALP 6/5/19 USMD Arlington Dr. R. Parham
      Cath 6 days, bladder spasms, cath back in for 5 days
      No incontinence/Minimum ED (using Sildenafil as needed)

      Final Path 6/11/19: G6(3+3)
      SV, BNI, Adipose Tissue, ECE, Margins, PNI, LVI, LNI(0of8) All Negative

      PT2N0 ~10% involved by tumor

      Quest Diagnostics uPSA:
      9/7/19 (3mths) <0.02
      1/4/20 (7mths) <0.1 & <0.02
      1/20/20 Annual physical <0.02
      6/6/20 (1yr) <0.02
      12/5/20(18mths) <0.02
      6/5/21(2Yr) <0.1
      1/17/22(31mths) 0.009-Clinical Path Lab ultrasensitive
      6/9/22(3 years)<0.04


      ​​​​
      ​​​​

      Comment

      • #4
        4 years ago I had an exam and removed a number of polyps all benign, last year went back for a 3 year and they removed maybe 2. Said they didn’t need for back for 5 years, going back in 4.
        YOB 1957

        DX 12/18, GS 8, 4+4 6/12 cores, LL Apex 100%, LM Apex 60%, LL Mid 50%, LMM 40%, LL Base 5%, LM &lt;5%, Right side negative.

        3/6/19. Post surgery Pathology Report - Grade Group 4 Intraductal Carcinoma
        T3aNO, <1 mm non focal EPE, GS8, 21 mm uni-focal tumor involved 10% of prostate.
        7 Nodes, SV, SM, PNI, and BNI were negative.
        LVI and Cribriform pattern present.
        Decipher .86 High Risk.

        Post Surgery PSA
        3/25/19 .03. (25 days)
        4/25/19 <.03. (2 months)
        5/25/19 <.02 (3 months)
        9/10/2019. <.02 (7 months)
        11/27/2019. <.02. T < 3 (9 months)
        5/19/2020. <.02 (15 months)
        11/2/2020. <.02 (21 months)
        5/11/2021. <.02 T <3 (27 months)
        8/25/2021. <.02 T <3 (30 months)
        12/6/2021. <.02 T <3 (33 months)
        6/14/2022. <.02 T <3 (39 months) T=37

        3 Part Modality Treatment Completed

        2/25/19 Robotic Laparoendoscopic Single Site Surgery outpatient Cleveland Clinic, Dr. Kaouk, surgery #41 in US.
        ART - 7/25/-9/25 2019 (78 Gy, yes, I glow in the dark).
        ADT - 5/19- 5/21 Eligard and Casodex.


        3 Part Modality Treatment Completed

        2/25/19 Robotic Laparoendoscopic Single Site Surgery outpatient Cleveland Clinic, Dr. Kaouk, surgery #41 in US.
        ART - 7/25/-9/25 2019 (78 Gy, yes, I glow in the dark).
        ADT - 5/19- 5/21 Eligard and Casodex.

        Comment

        • #5
          My first colo was in my mid fifties. Several polyps were removed. They were called "tubular adenoma", which my Dr described as being middle of the scale... not benign and potentially cancerous, but not the "bad" type. I think I've had three other colo's since then which were all clear. My gastro keeps extending the length of time between them as they continue to be negative. My most recent one was six months after completing adjuvant radiation, which is when I was diagnosed with radiation colitis. My next one will be in 2025 and that might be my last one ever, as I've heard that they stop recommending colo's for elderly males whose colo's have been negative.

          I still get endo's every three years because of my Barrett's esophagus. Originally that was every two years, but was increased because there has been no progression. I used to be able to time my endo's and colo's at the same time so as to only have to deal with one prep and one anesthesia, but the only least common multiple of 3 and 7 is 21 and in 21 years I'll be in my nineties.
          Late 2012: PSA 4, age 62 all DRE's 'normal'
          Early 2014: PSA 9.5, TRUS biopsy (false) negative
          2015: PSA's 12 & 20, lots of Cipro ... Mar '16: PSA 25, changed Urologist

          Jun'16: MRI fusion biopsy, RT base, 2ea 15-40-100% G8(4+4)
          Aug'16:DVRP, "broad cut" 11 LN-, neg margins, gland 53g, 25% involved
          multifocal EPE, PNI, BNI, bilateral SVI, pT3b N0          		 Dec 2016: Mrs: Dx stage 4 NHL/DLBCL, Primary Bone Lymphoma
          spinal RT boost+6X R-CHOP21+6X IT MTX via LP.
          Remission ended 2020, Follicular NHL. Currently active surveilance.

          Mar 2020: older adult son, T-cell acute lymphoblastic leukemia (TALL)
          Hyper-CVAD + pegaspargase, RBC transfusions in NYC amid COVID-19
          Bone marrow transplant Oct 2020, currently in Remission
          Jan'17: began Lupron ADT, uPSA's ~.03
          May'17: AMS800 implanted, revised 6/17
          Aug'17: 39 tx (70 Gy) RapidArc IGIMRT
          Jan 2018-Jan 2022: PSA's <0.008, T=50
          Apr'18: Dx radiation colitis, Oct'18: Tx sclerosing mesenteritis          		 June 2020: younger adult son, small bowel resection
          adenocarcinoma of lower ileum (SBA) w/+lymph node, stage T3a-N1
          Adjuvant chemo: 12x FOLFOX, currently in Remission

          "Everyone you meet is fighting a battle you cannot see"

          Comment

          • #6
            I had two polyps removed, the Dr said I had three things to do, fiber, fiber and more fiber.

            Sometimes I wonder if my septic tank is going to explode and send me into geosynchronous orbit.
            BD: 1959 PSA 4.9 11/2012 (no symptoms)
            Biopsy 12/2012 Negative
            PSA 5.9 05/2013 (still no symptoms)
            Biopsy 6/2013 3+4 (thank goodness for PSA tests)
            1 core positive (upper left), 1 suspicious (lower left) out of 12
            DRE: bump right side T1c; PCA-III = 20 (normala)

            Da Vinci 7/18/2013:
            Total prostatectomy with seminal vesicles (S13-6085, 1-29, 7/18/13, 29 H&E and 1 paraffin block)
            Invasive carcinoma involves left lobe of prostate only, extends from left apex to posterior mid region of left lobe Gleason 7/10 (4+3); G4 tumor comprises 75% of invasive carcinoma present
            Estimated total volume of carcinoma in entire prostate gland: 10%
            TNM: T2b NX MX (Stage IIA)

            PSA History:
            8/13 11/13 2/14 8/14 2/15 8/15 3/16, 8/16, 3/17,9/17,4/18, 9/18 PSA "undetectable" (PSA <.1)

            March '19 = 0.1
            April '19 = 0.10 <-- switched to uPSA tests
            June '19 = 0.10
            Sept '19 = 0.10
            Dec '19 = 0.09
            Jan '20 = 0.13
            May '20 = 0.2 <- standard test by mistake
            Jun '20 = 0.11 <- back to uPSA test
            Aug '20 = 0.16
            Jan '21 = 0.23
            Feb '21 =0.20
            Mar '21 - started ADT/HT, radiation scheduled
            Jun '21 Eight Weeks Radiation @MSKCC
            Jul '21 <.05 (T-Level 0)
            Feb '22 <.05 (T-Level back to normal)
            Aug '22 <.05 (T-Level still normal)

            Comment

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